产品详情 |
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Antigenic Specificity | NGFR |
Clone | ME20.4 |
Host Species | Mouse |
Reactive Species | canine, feline, human, nonhuman primate, porcine, rabbit |
Isotype | IgG1 |
Format | purified |
Size | 150 µg |
Concentration | lyophilized |
Applications | Immunocytochemistry: 2-10 µg/mL, Immunohistochemistry: 2-10 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NGFR Monoclonal Antibody (ME20.4). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Homodimer; disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and NGFRAP1/BEX3. |
Immunogen | n/a |
Other Names | Tumor necrosis factor receptor superfamily member 16, P08138, low-affinity nerve growth factor receptor, NGF receptor, Gp80-LNGFR, p75 ICD, low affini, p75, p-75 |
Gene, Accession # | Entrez: 100349095, 100525607, 101101519, 4804, 491071; Uniprot: P08138 |
Catalog # | OSM00018A |
Price | |
Order / More Info | NGFR Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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