| 产品详情 |
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| Product Name | BCR-RET Mutant, Active |
| Description | 1-426 (BCR) - 713-end (RET). MW: 140 kDa. Description: Recombinant human BCR-RET, the fusion protein [BCR (1-426)-RET (713-end)], was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: BCR-RET is a chimaeric fusion of BCR and RET genes generated by a balanced translocation of genes from t (10;22) (q11;q11) and this leads to aberrant activation of RET activity which can transform hematopoietic cells and skew the hematopoietic differentiation progra |
| Size | 0.005 mg, 0.01 mg |
| Concentration | n/a |
| Applications | Kinase Assay |
| Other Names | [Homo sapiens breakpoint cluster region, mRNA; Breakpoint cluster region protein; breakpoint cluster region protein; BCR, RhoGEF and GTPase activating protein; Renal carcinoma antigen NY-REN-26] |
| Gene, Accession, CAS # | BCR-RET, Gene ID: 613, Accession: BC066122 |
| Catalog # | MBS515646 |
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| Order / More Info | BCR-RET Mutant, Active from MYBIOSOURCE INC. |
| Product Specific References | 1. Ballerini, P. et al: RET fusion genes are associated with chronic myelomonocytic leukemia and enhance monocytic differentiation. Leukemia. 2012 Nov;26 (11):2384-9. |
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