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| Product Name | BDA-366 |
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| Description | Purity 98%. Small-molecule BDA-366 specifically targets the BH4 domain of Bcl2 BDA-366 suppresses human myeloma growth. BDA-366 induces robust apoptosis in MM cell lines and primary MM cells by inducing BCL2 conformational change. Delivery of BDA-366 substantially suppressed the growth of human MM xenografts in NOD-scid/IL2Rgammanull mice, without significant cytotoxic effects on normal hematopoietic cells or body weight. Thus, BDA-366 functions as a novel BH4-based BCL2 inhibitor and offers an |
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| Size | 5 mg, 1ml/10mM (In DMSO), 10 mg, 25 mg, 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CAS: 1821496-27-8 |
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| Catalog # | MBS578566 |
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| Price | |
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| Order / More Info | BDA-366 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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