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| Product Name | DPH2, 1-489aa, Human, His-tag, Baculovirus |
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| Description | Purity: > 85% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 1mM DTT, 20% glycerol.. DPH2, also known as diphthamide biosynthesis protein 2, is a homodimer and each of its monomers can bind a [4Fe-4S] cluster. It is the target of ADP ribosylating diphtheria toxin (DT) and Pseudomonas exotoxin A (PE). It was identified by its ability to complement a diphthamide mutant strain, and thus functions in diphthamide biosynthesis. Its loss pre-activates NF-kB and death receptor pathways and renders MCF7 cells hypersensitive to tumor necrosis factor. Recombinant human DPH2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
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| Size | 50ug, 10ug, |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Diphthamide biosynthesis protein 2, DPH2, DPH2L2 |
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| Gene, Accession, CAS # | NP 001375 |
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| Catalog # | ATGP3582 |
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| Order / More Info | DPH2, 1-489aa, Human, His-tag, Baculovirus from ATGen |
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| Product Specific References | n/a |
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