| 产品详情 |
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| Product Name | Recombinant Mouse Sonic hedgehog protein (Shh) (Active) |
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| Description | Purity > 95% as determined by SDS-PAGE and HPLC. MW: 19.8kDa. Partial: 26-198aa. tag-Free. Mus musculus (Mouse). Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO. {ECO:0000269|PubMed:14687547, ECO:0000269|PubMed:7736596}. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | SHH,,; Sonic hedgehog protein C-product Sonic hedgehog protein 27 kDa product,], |
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| Gene, Accession, CAS # | Shh,Hhg1, UniProt: Q62226 |
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| Catalog # | RPC26768 |
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| Price | |
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| Order / More Info | Recombinant Mouse Sonic hedgehog protein (Shh) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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