| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD312 |
|---|
| Clone | W15101A |
|---|
| Host Species | Rat |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG2a, κ |
|---|
| Format | purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry (FC), IHC-F |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Purified anti-human CD312 (EMR2). CD312, also known as Epidermal growth factor module-containing mucin-like receptor 2 (EMR2), is a 90 kD type I protein, a member of the Epidermal Growth Factor-seven transmembrane (EGF-TM7) family. Its extracellular region consists of five tandem EGF-like adhesion domains and a mucin-like stalk domain containing a G-protein proteolytic site, while the C-terminal region consists of a seven-pass transmembrane domain. CD312 is expressed by myeloid cells, dendritic cells, and activated lymphocytes. CD312 contributes to the interaction of macrophages, dendritic cells and activated T cells with B cells; it is involved in neutrophil chemotaxis, degranulation and adhesion, and release of inflammatory cytokines by macrophages. The ligands of CD312 are the glycosaminoglycans (GAG) chondroitin sulphate, and dermatan sulphate. |
|---|
| Immunogen | Recombinant protein fragment containing the first extracellular region of human EMR2 (24-540 a.a.). |
|---|
| Other Names | Epidermal growth factor module-containing mucin-like receptor 2, EMR2, AGRE2, ADGRE2 |
|---|
| Gene, Accession # | Gene ID: 30817 |
|---|
| Catalog # | 373102 |
|---|
| Price | |
|---|
| Order / More Info | CD312 Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|