| 产品详情 |
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| Antigenic Specificity | PDL2. Human PD-L2 / CD273 / B7-DC |
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| Clone | monoclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | unconjugated, no preservative |
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| Size | 50 ug, 100 ug |
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| Concentration | n/a |
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| Applications | ELISA, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Monoclonal to PDL2. Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins. PD-L2 and PD-L1 are two ligands for PD-1, a member of the CD28 protein family expressed on activated lymphoid cells, providing signals for regulating T cell activation and immune tolerance. PD-L2 is expressed on antigen presenting cells, placental endothelium and medullary thymic epithelial cells, and can be induced by lipopolysaccharide (LPS), a component of the cell wall in gram-negative bacteria, in B cells, INF-? in monocytes, or LPS plus IFN-? in dendritic cells. It has been demonstrated that on human T cells, PD-L2 acts only as a down regulator of T cell activity by inhibiting T-cell proliferation and the production of necessary cytokines. |
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| Immunogen | Recombinant human PD-L2 protein. |
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| Other Names | PD-L2 / CD273 / B7-DC |
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| Gene, Accession # | NCBI: NP_079515.2, UniProt: Q9BQ51 |
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| Catalog # | orb42959 |
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| Price | |
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| Order / More Info | PDL2. Human PD-L2 / CD273 / B7-DC Antibody from BIORBYT LTD. |
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| Product Specific References | n/a |
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