| 产品详情 |
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| Antigenic Specificity | CD273 (B7-DC) |
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| Clone | 176611 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2B |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Flow Cytometry: 2.5 µg/1x10^6 cells, Immunohistochemistry: 8-25 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD273 (B7-DC) Monoclonal Antibody (176611). Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist, this antibody is specific to the largest is |
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| Immunogen | n/a |
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| Other Names | PD-L2, B7DC, Btdc, PDCD1L2, PDL2, bA574F11.2, B7 dendritic cell molecule, B7-DC, PD-1 ligand 2, PD-1-ligand 2, PDCD1 ligand 2, butyrophilin B7-DC, programmed death ligand 2 |
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| Gene, Accession # | Entrez: 80380; Uniprot: Q9BQ51 |
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| Catalog # | MA5-23887 |
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| Price | |
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| Order / More Info | CD273 (B7-DC) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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