| 产品详情 |
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| Antigenic Specificity | CD86 |
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| Clone | 24F |
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| Host Species | Mouse |
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| Reactive Species | rat |
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| Isotype | IgG1 |
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| Format | fluorescein (FITC) conjugate |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | Flo (1:1 - 1:10) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD86 Antibody (clone 24F, FITC) LS-C188423. Recognizes rat CD86, otherwise known as B7-2, a type I transmembrane protein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells, and also on germinal centre B cells and macrophages. Like CD80, CD86 is an accessory molecule which functions in the CD28-CD80/CD86 co-stimulatory pathway, vital for T cell activation, crosstalk between T and B cells, and Th2-mediated Ig production. Clone 24F has been shown to block the co-stimulatory activity of rat CD86. |
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| Immunogen | HTLV-1 transformed Lewis-S1 cells. |
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| Other Names | CD86, Activation B7-2 antigen, B7-2, B7.2, B70, CD86 molecule, CTLA-4 counter-receptor B7.2, CD86 antigen, FUN-1, LAB72, BU63, CD28LG2, Ctla-4 counter-receptors b7.2 |
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| Gene, Accession # | CD86, Gene ID: 942 |
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| Catalog # | LS-C188423 |
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| Price | |
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| Order / More Info | CD86 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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