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| Product Name | FLT3-ITD-W51 Mutant, Active |
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| Description | 571-993 (FLT3-ITD-W51). MW: 76 kDa. Description: Recombinant human FLT3-ITD-W51 (571-993) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: Fms-related tyrosine kinase 3 (FLT3) is a gene that encodes for a tyrosine kinase that activates pathways in hematopoietic cells important in cellular proliferation. FLT3 is frequently mutated in acute myeloid leukemia (AML), myelodysplastic syndromes, other hematologic malignancies, and colorectal cancer |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | Kinase Assay |
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| Other Names | [FLT3-ITD-NPOS Mutant, Active ] |
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| Gene, Accession, CAS # | FLT3-ITD-W51, Gene ID: 2322, Accession: NM_004119.2 |
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| Catalog # | MBS515503 |
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| Order / More Info | FLT3-ITD-W51 Mutant, Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. http://www.mycancergenome.org/content/disease/acute-myeloid-leukemia/flt3/277/ 2. Fathi AT, et al: Treatment of FLT3-ITD acute myeloid leukemia. Am J Blood Res. 1 (2):175-89, 2011 |
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