产品名称 HLA-DP+DQ+DR Antibody from LIFESPAN BIOSCIENCES INC.
产品货号 LS-C751173
产品价格 现货询价,电话:010-67529703
产品规格 n/a
产品品牌 LIFESPAN BIOSCIENCES INC.
产品概述
产品详情
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Antigenic SpecificityHLA-DP+DQ+DR
CloneHLA-DPB1/2967R
Host SpeciesRecombinant Rabbit
Reactive Specieshuman
IsotypeIgG
FormatProtein A/G purified
Sizen/a
Concentrationn/a
ApplicationsIHC-Fx, SDS-PAGE
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DescriptionHLA-DP+DQ+DR Antibody (clone HLA-DPB1/2967R) LS-C751173. Specificity: Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an i! chain (36 kDa ) and a ic chain (27 kDa ). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six i! and ten ic chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
ImmunogenNon-T, non-B human acute lymphoblastic leukemia REH6 cell line. Antigen Molecular Weight: 33-35 kDa
Other Namesn/a
Gene, Accession #n/a
Catalog #LS-C751173
Price
Order / More InfoHLA-DP+DQ+DR Antibody from LIFESPAN BIOSCIENCES INC.
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