| 产品详情 |
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| Antigenic Specificity | Mac-2 (Galectin-3) |
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| Clone | Gal397 |
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| Host Species | Mouse |
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| Reactive Species | human, African green, baboon, cynomolgus, mouse |
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| Isotype | IgG1, κ |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB), ICC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-mouse/human Mac-2 (Galectin-3). Galectin-3 (galactose-specific lectin 3) is a glycoprotein, also known as Mac-2, Gal-3, RL-29, galactose-specific lectin 3, CBP-35, L-34, and εBP. It is a member of animal β-galactoside-binding protein family that is expressed in cell nucleus, cytoplasm, plasma membrane, or extracellular matrix by variety of tumor cells, monocytes/macrophages, epithelial cells, Kupffer cells, and dendritic cells. Galectin-3 contains carbohydrate recognition domains and binds to β-galactoside residues bearing glycoproteins, such as as IgE, IgA, galactose, casein kinase I, laminin, mucin, LAMPs, and CD66. Galectin-3 is an adhesion molecule and plays an important role in regulation of cell proliferation, differentiation and tumor cell metastasis. Galectin-3 structurely possesses NWGR motif that is conserved in BH-1 domain of BCL-2 family and functions as an anti-apoptotic molecule. |
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| Immunogen | Recombinant (partial), amino acids 151-251 |
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| Other Names | Galectin-3, Mac-2 |
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| Gene, Accession # | Gene ID: 16854, 3958 |
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| Catalog # | 126701 |
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| Price | |
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| Order / More Info | Mac-2 (Galectin-3) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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