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| Product Name | SD 208 |
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| Description | Potent, orally active ATP-competitive transforming growth factor-β receptor 1 (TGF-βRI) inhibitor (IC50 = 49 nM). Displays > 100-fold and > 17-fold selectivity over TGF-βRII and other common kinases respectively. Exhibits anti-inflammatory and antitumor activity. Also promotes an antiglioma immune response. Ameliorates germinal matrix hemorrhage-induced neurological deficits in neonatal rats. Purity 98%. MW (observed): 352.75 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-(5-Chloro-2-fluorophenyl)-4-[(4-pyridyl)amino]pteridine |
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| Gene, Accession, CAS # | CAS: 627536-09-8 |
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| Catalog # | 3269/10 |
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| Order / More Info | SD 208 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 20871099, 21851806, 21873546, 22268139, 22844446, 26963853, 27163626, 29773599 |
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