| 产品详情 |
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| Antigenic Specificity | MINA |
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| Clone | 1H6B44 |
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| Host Species | Rat |
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| Reactive Species | human |
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| Isotype | IgG2a, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB), ICC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-MINA. MINA, also known as Mineral dust-induced gene (MDIG), is a member of the JmjC family of proteins and can act as a histone lysine demethylase and a ribosomal histidine hydroxylase. MINA is implicated in the demethylation of K9 trimethylated histone H3 (H3K9me3), regulating cell proliferation and survival. MINA has been suggested to be a novel oncogene associated with a variety of cancers. Elevated expression of MINA in human tumors has been linked to malignancy and poor prognosis. MINA has been identified as a transcriptional co-repressor of IL-4 gene and participates in the regulation of Th2 differentiation and Th2 bias. MINA appears to be a regulator of the Treg/Th17 balance by promoting differentiation of Th-17 cells and inhibiting FOXP3 expression. |
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| Immunogen | Partial recombinant protein (300-465 aa) expressed in E. coli. |
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| Other Names | Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA, 60S ribosomal protein L27a histidine hydroxylase, Histone lysine demethylase MINA, MYC-induced nuclear antigen, Nucleolar protein 52 (NO52), Ribosomal oxygenase MINA (ROX), MDIG |
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| Gene, Accession # | Gene ID: 84864 |
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| Catalog # | 683302 |
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| Price | |
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| Order / More Info | MINA Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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