| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | IL-21 |
|---|
| Clone | 7H20-I19-M3 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, mouse |
|---|
| Isotype | IgG1, κ |
|---|
| Format | biotin conjugate |
|---|
| Size | 50 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot (WB), Immunofluorescence Microscopy (IF) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Biotin anti-human/mouse IL-21. Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Recent studies have shown that IL-21 is also an autocrine cytokine that potently induces T(H)17 differentiation and suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases. |
|---|
| Immunogen | Recombinant full length human IL-21 |
|---|
| Other Names | Interleukin 21 |
|---|
| Gene, Accession # | Gene ID: 59067, 60505 |
|---|
| Catalog # | 514303 |
|---|
| Price | |
|---|
| Order / More Info | IL-21 Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|