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| Antigenic Specificity | DOK1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DOK1 Polyclonal Antibody. DOK1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. DOK2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling. |
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| Immunogen | n/a |
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| Other Names | p62(dok), Downstream of tyrosine kinase 1, pp62 |
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| Gene, Accession # | Entrez: 1796; Uniprot: Q99704 |
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| Catalog # | PA5-14752 |
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| Price | |
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| Order / More Info | DOK1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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