| 产品详情 |
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| Product Name | PF-562271 besylate |
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| Description | MW: 665.66. Purity ≥98% by HPLC. F-562271 is an ATP-competitive; reversible inhibitor of FAK (IC50 = 1.5 nM). It displays 10-fold reduced potency for PYK2 (IC50 = 14 nM) and >100-fold selectivity against other protein kinases. PF-562271 inhibits FAK phosphorylation with an EC?? value of 93 ng/ml in glioblastoma-bearing mice and has been shown to regress tumors in multiple xenograft models. |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [N-[3-[[[2-[ (2; 3-dihydro-2-oxo-1H-indol-5-yl) amino]-5- (trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methyl-methanesulfonamide; monobenzenesulfonate] |
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| Gene, Accession, CAS # | CAS: 939791-38-5 |
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| Catalog # | MBS846395 |
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| Price | |
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| Order / More Info | PF-562271 besylate from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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