| 产品详情 |
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| Antigenic Specificity | ROR gamma (t) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, nonhuman primate |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: Assay-Dependent, Immunofluorescence: Assay-Dependent, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 2.5-10 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ROR gamma (t) Polyclonal Antibody. ROR-gamma is a 560 amino acid novel DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. The specific functions of this protein are not known. However, reports suggest that this protein is a ligand activated transcription factor and may be essential for lymphoid organogenesis (lymph nodes and Peyer's patches) and may play an important regulatory role in controlling apoptosis during thymopoiesis. ROR-gamma inhibits the expression of Fas ligand and IL2 and directs the differentiation program of proinflammatory IL-17+ T helper cells. ROR-gamma shares 50 to 51% sequence identity with RORA and RORB and is 88% identical to mouse ROR-gamma. It is highly expressed in skeleta |
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| Immunogen | n/a |
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| Other Names | RP11-98D18.11-001, NR1F3, RORG, RZR-GAMMA, RZRG, TOR, RAR-related orphan nuclear receptor variant 2, nuclear receptor ROR-gamma, nuclear receptor RZR-gamma, nuclear receptor subfamily 1 group F member 3, retinoic acid-binding receptor gamma, retinoid-related orphan receptor gamma |
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| Gene, Accession # | Entrez: 19885, 6097; Uniprot: P51449, P51450 |
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| Catalog # | PA5-23148 |
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| Order / More Info | ROR gamma (t) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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