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| Product Name | Recombinant Human TAR DNA-binding protein 43 |
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| Description | 1-396.Fragment at the N-terminal. MW: 58.89kD. Purity >90% as determined by SDS-PAGE. DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cel |
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| Size | 0.01 mg (E-Coli), 0.01 mg (Yeast), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [TAR DNA-binding protein 43; TAR DNA-binding protein 43; TAR DNA-binding protein 43; TAR DNA binding protein] |
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| Gene, Accession, CAS # | TARDBP, Gene ID: 23435, Accession: NP_031401.1 |
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| Catalog # | MBS1265560 |
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| Order / More Info | Recombinant Human TAR DNA-binding protein 43 from MYBIOSOURCE INC. |
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| Product Specific References | Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs.Ou S.-H.I., Wu F., Harrich D., Garcia-Martinez L.F., Gaynor R.B.J. Virol. 69:3584-3596(1995) TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein.Strong M.J., Volkening K., Hammond R., Yang W., Strong W., Leystra-Lantz C., Shoesmith C.Mol. Cell. Neurosci. 35:320-327(2007) Complete sequencing and characterization of 21,243 full-leng |
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