| 产品详情 |
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| Antigenic Specificity | alpha-1b Adrenergic Receptor |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:100-1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | alpha-1b Adrenergic Receptor Polyclonal Antibody. Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. |
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| Immunogen | n/a |
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| Other Names | ADRA1, ALPHA1BAR |
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| Gene, Accession # | Entrez: 147; Uniprot: P35368 |
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| Catalog # | PA1-32558 |
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| Price | |
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| Order / More Info | alpha-1b Adrenergic Receptor Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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