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| Antigenic Specificity | STUB1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | STUB1 Polyclonal Antibody. CHIP is an E3 ligase for nNOS whose action is facilitated by (and possibly requires) its interaction with nNOS-bound hsp70. Co-chaperone CHIP, possibly with another E3 ligase(s), modulates the ubiquitylation of mutant Cu/Zn-superoxide dismutase and renders them more susceptible for proteasomal degradation. CHIP functions as a negative regulator of AR transcriptional activity by promoting AR degradation. CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival. CHIP can interact with the Smad1/Smad4 proteins and block BMP signal transduction through the ubiquitin-mediated degradation of Smad proteins. CHIP E3 controls both the association of Hsp70/Hsp90 chaperones with ErbB2 and the down-regul |
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| Immunogen | n/a |
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| Other Names | Carboxy terminus of HSP70-interacting protein; CLL-associated antigen KW-8; STIP1 homology and U-Box containing protein 1; STUB1 |
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| Gene, Accession # | Entrez: 10273; Uniprot: Q9UNE7 |
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| Catalog # | PA5-13419 |
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| Price | |
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| Order / More Info | STUB1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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