| 产品详情 |
| Edit |   |
| Antigenic Specificity | SIGLEC9 |
| Clone | K8 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | purified |
| Size | 100 µg |
| Concentration | n/a |
| Applications | ELISA: Assay-dependent, Flow Cytometry: Assay-dependent, Immunofluorescence: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SIGLEC9 Monoclonal Antibody (K8). Siglec9 (Sialic acid-binding Ig-like lectin 9) is single-pass type I membrane protein and belongs to immunoglobulin super family and contains two Ig-like C2 type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. It is reported that Siglec9 recognizes sialic acid in alpha2, 3-or alpha2, 6-glycosidic linkage to galactose. Using a specific antibody, Siglec9 was found to be expressed at high or intermediate levels by monocytes, neutrophils, and a minor population of CD16+, CD56- cells. Siglec9 also acts as an inhibitory receptor for MUC16 that attenuates T- andNK cell function. Recent reports suggest that Siglec9 expressed on DCs is involved in immuno regulation through ligation |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | Entrez: 27180; Uniprot: Q9Y336 |
| Catalog # | MA5-28203 |
| Price | |
| Order / More Info | SIGLEC9 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
| 产品资料 |
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