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| Product Name | Recombinant Human herpesvirus 1 Tegument protein VP16 (UL48) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 70.3kDa. Full Length: 1-490aa. N-terminal 6xHis-SUMO-tagged. Human herpesvirus 1 (strain F) (HHV-1) (Human herpes simplex virus 1). Transcriptional activator of immediate-early (IE) gene products (alpha genes). Acts as a key activator of lytic infection by initiating the lytic program through the assembly of the transcriptional regulatory VP16-induced complex composed of VP16 and two cellular factors, HCFC1 and POU2F 1. VP16-induced complex represents a regulatory switch: when it is on, it promotes IE-gene expression and thus lytic infection, and when it is off, it limits IE-gene transcription favoring latent infection (By similarity).By similarity1 Publication May play a role in the aggregation of tegument proteins around nucleocapsids during virus morphogenesis. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Alpha trans-inducing protein; Alpha-TIF; ICP25; Vmw65 |
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| Gene, Accession, CAS # | UL48, UniProt: P04486 |
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| Catalog # | RPC22680 |
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| Order / More Info | Recombinant Human herpesvirus 1 Tegument protein VP16 (UL48) from BIOMATIK |
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| Product Specific References | n/a |
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