| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | ESR2 / ER Beta, aa493-504 |
|---|
| Clone | 5/25 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | Protein G purified |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | IHC, IHC-P, WB |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | ESR2 / ER Beta Antibody (aa493-504, clone 5/25) LS-C188515. Recognizes human estrogen receptor beta 5 (ERB5), a splice variant of the nuclear receptor hormone ERbeta (ESR2), shown to exist in at least five isoforms (ERB1-ERB5). Although only the ERB1 variant appears fully functional, the remaining isoforms have been shown to form heterodimers with ERB1, thereby enhancing transcription. Immunohistochemical studies have revealed a ubiquitous expression of ERB5 in normal colorectal tissue, and to be present in all primary colorectal carcinomas studied. Studies also revealed the nuclear expression of ERB5 in the majority of breast carcinomas tested, with a possible association with improved patient survival. |
|---|
| Immunogen | Tuberculin conjugated synthetic peptide LLSHVRHARYAP derived from the C-terminus of human ERB5. Percent identity by BLAST analysis: Human (100%); Ferret (92%). |
|---|
| Other Names | ESR2, ESTRB, ER Beta, ERbeta, ER-BETA, ESR-BETA, ESRB, Estrogen receptor 2 (ER beta), NR3A2, Estrogen receptor beta, Estrogen receptor beta 4 |
|---|
| Gene, Accession # | ESR2, Gene ID: 2100 |
|---|
| Catalog # | LS-C188515 |
|---|
| Price | |
|---|
| Order / More Info | ESR2 / ER Beta, aa493-504 Antibody from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|