| 产品详情 |
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| Product Name | LDN-193189 |
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| Description | Inhibits BMP type 1 receptor-induced phosphorylation of SMAD1/5/8 (IC50 = 4.9 nM); shows specificity for ALK1, 2, 3, and 6 (IC50s = 0.8, 0.8, 5.3, and 16.7 nM, respectively) over ALK4 and 5 (IC50s = 101 and 350 nM, respectively) |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | DM-3189 SMADs SMAD1/5/8 BMP bones morphogenetics proteins TGF-β inhibitors ALK1 ALK2 ALK3 ALK6 cancers formations ALK-1 ALK-2 ALK-3 ALK-3 ALK-6 ALKs SMAD-1/5/8 TGF-beta TGF-.beta. TGF-b TGFs LDN-193189 LDN193189 inhibits inhibitions drosophila mothers against decapentaplegic Mad genes C. delegans Sma activin receptors like kinases receptor-like in vitro kinases type I one fibrodysplasia ossificans hyperossification disorders osteogenesis prostates tumors metastases DM3189 DM 3189 transcriptions factors bone-related intracellular signaling |
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| Gene, Accession, CAS # | CAS: 1062368-24-4 |
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| Catalog # | 11802-10 |
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| Price | |
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| Order / More Info | LDN-193189 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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