| 产品详情 |
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| Antigenic Specificity | CD86 |
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| Clone | rC86/1146 |
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| Host Species | Recombinant Mouse |
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| Reactive Species | human |
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| Isotype | IgG1,k |
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| Format | azide-free unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC-Fx, SDS-PAGE |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD86 Antibody (clone rC86/1146, Azide-free) LS-C751453. Recognizes a protein of 70 kDa , which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease. |
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| Immunogen | Recombinant full-length human CD86 protein. Antigen Molecular Weight: 70 kDa |
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| Other Names | CD86, Activation B7-2 antigen, B7-2, B7.2, B70, CD86 molecule, CTLA-4 counter-receptor B7.2, CD86 antigen, FUN-1, LAB72, BU63, CD28LG2, Ctla-4 counter-receptors b7.2 |
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| Gene, Accession # | CD86, Gene ID: 942 |
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| Catalog # | LS-C751453 |
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| Price | |
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| Order / More Info | CD86 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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