产品详情 |
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Antigenic Specificity | CD86 |
Clone | BU63 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein A purified |
Size | n/a |
Concentration | n/a |
Applications | Flo (1:20 - 1:100), IHC, IHC-Fr (1:20 - 1:100), IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD86 Antibody (clone BU63) LS-C43296. Recognizes human CD86 also known as B7-2, a type I transmembrane protein expressed by monocytes and activated B cells. CD86 acts as a co-stimulatory molecule along with CD80 and is a ligand for CD28 and CTLA-4. CD86 is a member of the Immunoglobulin superfamily and carries an extracellular domain bearing both an domain which contains the CTLA-4 binding site and an adjacent C2-like domain. CD86 plays an important role in co-stimulation of T cell proliferation, IL-2 production and in the primary immune response. Domain depletion epitope mapping studies indicate that the binding site of Mouse anti Human CD86, is located within the Ig-v-like domain of human CD86. Studies suggest that CD86 along with CD80 may be exploited as receptors for adenovirus entry into cells. |
Immunogen | Human peripheral blood lymphocytes. |
Other Names | CD86, Activation B7-2 antigen, B7-2, B7.2, B70, CD86 molecule, CTLA-4 counter-receptor B7.2, CD86 antigen, FUN-1, LAB72, BU63, CD28LG2, Ctla-4 counter-receptors b7.2 |
Gene, Accession # | CD86, Gene ID: 942 |
Catalog # | LS-C43296 |
Price | |
Order / More Info | CD86 Antibody from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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