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| Product Name | CDK8, Unactive Recombinant protein |
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| Description | MW: ~84 kDa. Purity >80%. Recombinant full-length human CDK8 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: CDK8 is a member of the CDK family which are important regulators of cell cycle progression. CDK8 associates with Cyclin C and is a component of the RNA polymerase II holoenzyme complex that phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II (1). CDK8 regulate transcription by targ |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | 0.2ug/ul |
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| Applications | Kinase Assay, Western Blot (WB) |
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| Other Names | [K35; MGC126074; MGC126075; CDK8; Unacitve] |
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| Gene, Accession, CAS # | CDK8, Gene ID: 1024, Accession: BC069634 |
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| Catalog # | MBS515108 |
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| Order / More Info | CDK8, Unactive Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1.Akoulitchev S, et al: TFIIH is negatively regulated by cdk8-containing mediator complexes. Nature 407: 102-106, 2000. 2.Firestein R, et al: CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. Nature 455: 547-551, 2008. |
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