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| Product Name | MitoPT TMRE Mitochondrial Depolarization Assay Kit |
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| Description | Description: ICT's MitoPT TMRE Assay utilizes a well-characterized potentiometric fluorescent dye to detect mitochondrial membrane depolarization: tetramethylrhodamine ethyl ester, commonly known as TMRE. The lipophilic structure of TMRE allows it to easily penetrate cell and mitochondrial lipid bilayer membrane barriers. As a member of the rhodamine family of potentiometric dyes, TMRE will distribute itself within healthy, polarized mitochondria in a Nernstian manner. When accumulated in negati |
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| Size | 500 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | MitoPT TMRE |
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| Catalog # | MBS258009 |
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| Order / More Info | MitoPT TMRE Mitochondrial Depolarization Assay Kit from MYBIOSOURCE INC. |
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| Product Specific References | Plasek, J. and K. Sigler. 1996. Slow fluorescent indicators of membrane potential: a survey of different approaches to probe response analysis. J. Photoch. Photobio. B. 33: 101-124. Ehrenberg, B., V. Montana, M. Wei, J.P. Wuskell, and L.M. Loew. 1988. Membrane potential can be determined in individual cells from the Nernstian distribution of cationic dyes. Biophys. J. 53: 785-794. Waggoner, A.S. 1979. Dye indicators or membrane potential. Ann Rev. Biophys. Bioeng. 8: 47-68. Scaduto, R.C. and L.W. Grotyohann. 1999. Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives. Biophys. J. 76: 469-477. Jayaraman, S. 2005. Flow cytometric determination of mitochondrial membrane potential changes during apoptosis of T lymphocytic and pancreatic bet cell lines: Comparison of tetramethylrhodamineethylester (TMRE), chloromethyl-X-rosamine (H2-CMK-Ros) and mito tracker red 580 (MTR580). J. Immunol. Methods 306: 68-79. |
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