| 产品详情 |
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| Antigenic Specificity | NUP50 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NUP50 Polyclonal Antibody. The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. NUP50 may serve as a binding site on the nuclear side of the pore complex for export receptor-cargo complexes. It interacts with multiple transport receptor proteins including p27Kip1. This interaction is required for correct intracellular transport and degradation of p27Kip1. |
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| Immunogen | n/a |
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| Other Names | Nucleoporin 50kDa; isoform a; NUP50 protein; NUP50; |
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| Gene, Accession # | Entrez: 10762, 18141; Uniprot: Q9JIH2, Q9UKX7 |
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| Catalog # | PA5-11742 |
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| Price | |
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| Order / More Info | NUP50 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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