| 产品详情 |
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| Antigenic Specificity | CAS |
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| Clone | P5111 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CAS Monoclonal Antibody (P5111). Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq]. |
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| Immunogen | n/a |
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| Other Names | CAS, XPO2, CSE1 chromosome segregation 1-like yeast, CSE1 |
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| Gene, Accession # | Entrez: 110750, 1434, 362273; Uniprot: P55060, Q9ERK4 |
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| Catalog # | MA5-18301 |
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| Price | |
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| Order / More Info | CAS Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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