| 产品详情 |
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| Product Name | MKC-3946 |
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| Description | An inhibitor of IRE1α; inhibits ER stress induced XBP1 splicing and reduces expression of the XBP1 target genes SEC61A1, p58IPK, and ERdj4 in RPMI 8226 cells; cytotoxic to multiple myeloma cell lines but has no effect on normal mononuclear cells; reduces tumor growth and XBP1 splicing in an RPMI 8226 mouse xenograft model (100 mg/kg) |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MKC3946 XBP-1 IRE RPMI8226 |
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| Gene, Accession, CAS # | CAS: 1093119-54-0 |
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| Catalog # | 19152-10 |
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| Price | |
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| Order / More Info | MKC-3946 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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