产品详情 |
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Antigenic Specificity | CD243 (ABCB1) |
Clone | 4E3.16 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | purified |
Size | 1 ml |
Concentration | n/a |
Applications | IHC, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-CD243 (ABCB1). CD243 (also known as ABCB1, MDR-1, and P-glycoprotein 1) is an ATP-dependent protein found in the cell membrane, and acts as an efflux pump to transport various substances across the cell membrane and out of cells. CD243 is a member of the MDR/TAP family, whose members are involved in the development of multidrug resistance. CD243 also acts as a transporter in the blood-brain barrier. |
Immunogen | This antibody was raised against a multidrug-resistant human squamous lung cancer cell line SW-1573/500 (Doxorubicin resistant). |
Other Names | MDR-1, Multidrug resistance protein 1, P-glycoprotein 1, colchicin sensitivity, doxorubicin resistance, SIG-38740-1000 |
Gene, Accession # | Gene ID: 5243 |
Catalog # | 919401 |
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Order / More Info | CD243 (ABCB1) Antibody from BIOLEGEND |
Product Specific References | PubMed: 8674056 |
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