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Product Name | (+)-Bicuculline (GABAA Receptor Antagonist, Bicuculline) |
Description | Purity ~99% (HPLC). A potent allosteric antagonist of vertebrate GABAA receptors. Blocks GABAA-induced chloride currents in cultured neurons (IC50 = 740nM). Shown to increase blood pressure in spontaneously hypertensive rats and cause convulsion in experimental animals. Also, increases the amplitude of spontaneous colonic contractions. Primary Target: GABA-A Primary Target IC50: 740Nm Solubility: DMSO |
Size | 50mg |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | 217220 |
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Order / More Info | (+)-Bicuculline (GABAA Receptor Antagonist, Bicuculline) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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