| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD24 Molecule (CD24) |
|---|
| Clone | SN3 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | phycoerythrin (PE) conjugate |
|---|
| Size | 100 tests |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry (FACS) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4, it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid. |
|---|
| Immunogen | Glycoproteins purified from human NALM-1 cell line. |
|---|
| Other Names | CD24A|Cd24a|Cd24|HSA|Ly-52|nectadrin |
|---|
| Gene, Accession # | Gene ID: 100133941 |
|---|
| Catalog # | ABIN192414 |
|---|
| Price | |
|---|
| Order / More Info | CD24 Molecule (CD24) Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | PubMed: 17980703, 17680316, 17700640, 16390867, 11313396, 3493967, 2153173, 1370683, 25578543, 22819865, 3489635 |
|---|
| 产品资料 |
|
|