产品详情 |
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Antigenic Specificity | MMP-9 |
Clone | L51/82 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | IHC, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-MMP-9. Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within the extracellular matrix. The MMP family includes different groups of enzymes, such as, collagenases, gelatinases, stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to be cleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thought to play an important role in tissue remodeling associated with various physiological and pathological processes. MMP9 degrades proteins in the extracellular matrix and activates growth factors like proTGFb and proTNFa. MMP-9 contributes to the invasion and metastasis of various human malignancies. Clone F11P2C3 has been shown to be useful for western blotting and immunohistochemistry of human MMP9. |
Immunogen | This monoclonal antibody was raised against a full-length fusion protein corresponding to amino acids 1-708 of rat MMP9 protein. |
Other Names | GELB, MMP9, gelatinase B, 92 kDa gelatinase, 92 kDa type IV collagenase, 92-kDa type IV collagenase, matrix metalloproteinase 9 (gelatinase B 92-kDa type IV collagenase), matrix metalloproteinase 9 (gelatinase B, 92-kDa type IV collagenase), MMS-5163-100 |
Gene, Accession # | Gene ID: 81687 |
Catalog # | 819701 |
Price | |
Order / More Info | MMP-9 Antibody from BIOLEGEND |
Product Specific References | n/a |
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