产品名称 Non-cleavable Linker from CREATIVE BIOLABS
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产品价格 现货询价,电话:010-67529703
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产品品牌 CREATIVE BIOLABS
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Product NameNon-cleavable Linker
DescriptionCreative Biolabs can provide several noncleavable alkyl and polymeric linkers, such as the notablely successful MCC amine-to-sulfhydryl bifunctional cross-linker featured in T-DM1. This linker is especially useful as the cyclohexane ring provides steric hindrance that decreases the rate of hydrolysis of the resulting thioether. Non-cleavable thioether linkers, succinimide-thioether bonds that formed by the reaction of maleimids with thiols, have also been commonly used to link auristatin derivatives to monoclonal antibodies.
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Order / More InfoNon-cleavable Linker from CREATIVE BIOLABS
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