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Product Name | FOLH, Recombinant, Human, aa48-750, His-Tag (Glutamate Carboxypeptidase 2) |
Description | Purity ~90% (SDS-PAGE). Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC. Source: Recombinant protein corresponding to aa48-750 from human Glutamate Carboxypeptidase 2, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~83.1kD AA |
Size | 10ug, 50ug, 100ug |
Concentration | n/a |
Applications | n/a |
Other Names | Cell growth-inhibiting gene 27 protein, Folate hydrolase 1 Folylpoly-gamma-glutamate carboxypeptidase, FGCP Glutamate carboxypeptidase II, GCPII Membrane glutamate carboxypeptidase, mGCPN-acetylated-alpha-linked acidic dipeptidase I, NAALADase I Prostate-specific membrane antigen, PSM, PSMA Pteroylpoly-gamma-glutamate carboxypeptidase |
Gene, Accession, CAS # | SwissProt: Q04609 |
Catalog # | 373359 |
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Order / More Info | FOLH, Recombinant, Human, aa48-750, His-Tag (Glutamate Carboxypeptidase 2) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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