| 产品详情 |
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| Product Name | Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) peptide |
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| Description | Psmd10 acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly,Psmd10 is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module By similarity.Psmd10 acts as an oncoprotein by being involved in negative regulation of tumor suppressors RB1 and p53/TP53. Overexpression of this gene is leading to phosphorylation of RB1 and proteasomal degradation of RB1. Psmd10 regulates CDK4-mediated phosphorylation of RB1 by competing with CDKN2A for binding with CDK4. |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
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| Other Names | gankyrin|zgc:109707|dJ889N15.2|p28|p28(GANK)|AW554874|p28Gank |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN939740 |
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| Price | |
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| Order / More Info | Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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