| 产品详情 |
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| Product Name | Cl-Amidine (hydrochloride) |
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| Description | A pan PAD inhibitor (IC50s = 0.8, 6.2, and 5.9 µM for PAD1, PAD3, and PAD4, respectively, in vitro); irreversibly inactivates PAD4 (kinact/KI = 13,000 M-1min-1) and PAD3 (kinact/KI = 2,000 M-1min-1); cytotoxic to HL-60, MCF7, and HT-29 cancer cell lines (IC50s = 0.25, 0.05 and 1 µM, respectively), |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | inhibitors PAD4 cancers epigenetics amidines proteins arginine deiminase 4 arthritis PADs cytotoxic HL-60 HL60 HT-29 mice joints auto antibodies HL 60 MCF7 MCF-7 HT29 citrulline IgG HT 29 cells lines ClA mouse serum autoantibodies auto-antibodies PAD3 PAD1 1043444-18-3 913723-61-2 |
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| Gene, Accession, CAS # | CAS: 1373232-26-8 |
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| Catalog # | 10599-10 |
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| Price | |
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| Order / More Info | Cl-Amidine (hydrochloride) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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