产品详情 |
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Antigenic Specificity | ACO1 (Phosphorylated S711) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | IF, IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit Anti-ACO1 (Phosphorylated S711) Polyclonal Antibody (PTM-CBPAB-0062YC). Provided herein is a Rabbit polyclonal antibody against Aconitase 1. The antibody can be used for immunoassay techniques, such as IF, IHC-P. ACO1 is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA |
Immunogen | KLH conjugated phosphopeptide, human Aconitase 1 around Ser711 [YG(p-S)RR] |
Other Names | Aconitase 1; Iron-Responsive Element-Binding Protein 1; Aconitate Hydratase, Cytoplasmic; Ferritin Repressor Protein; Iron Regulatory Protein 1; Cytosplasmic Aconitase; Aconitase 1, Soluble; Citrate Hydro-Lyase; Soluble Aconitase; EC 4.2.1.3; IRE-BP 1; |
Gene, Accession # | Gene ID: 48, UniProt: P21399 |
Catalog # | PTM-CBPAB-0062YC |
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Order / More Info | ACO1 (Phosphorylated S711) Antibody from CREATIVE BIOLABS |
Product Specific References | n/a |
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