| 产品详情 |
| Edit |   |
|---|
| Product Name | GNE-0877 |
|---|
| Description | A selective, brain-penetrable LRRK2 inhibitor (Ki = 0.7 nM); inhibits LRRK2 Ser1292 autophosphorylation in BAC transgenic mice expressing human LRRK2 protein with the G2019S Parkinson's disease mutation (IC50 = 3 nM in vivo) |
|---|
| Size | 5 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | neuroscience Leucine-rich repeat kinase 2 LRRK2 inhibitor Parkinson's disease mutation biochemical inhibit selective GNE0877 brain-penetrable Ser1292 Ser 1292 autophosphorylation protein G2019S in vivo |
|---|
| Gene, Accession, CAS # | CAS: 1374828-69-9 |
|---|
| Catalog # | 16251-5 |
|---|
| Price | |
|---|
| Order / More Info | GNE-0877 from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|