| 产品详情 |
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| Product Name | LYS6K2 |
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| Description | MW: 445.4. Purity 98% (TLC: 5% CH3OH3 in CH2Cl2, Rf=0.43); NMR (Conforms). S6K InhibitorPotent and selective inhibitor of glycogen synthase kinase-3 (GSK-3) IC50=5 nM1. The first pharmacological agent shown to maintain self-renewal in human and mouse embryonic stem cells2. Promotes proliferation in mammalian cardiomyocytes2 A potent inhibitor of malignant lymphoid cell proliferation3.Scientific Background: A selective inhibitor of the p70 ribosomal S6 kinase (S6K) (1). Blocks |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [6BIO; (2'Z,3'E)-6-Bromoindirubin-3'-oxime; 4-(4-(4-(4-fluoro-3-(trifluoromethyl) phenyl)-1-methyl-1H-imidazol-2-yl) piperidin-1-yl)-1H-pyrazolo [3,4-d] pyrimidine] |
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| Gene, Accession, CAS # | CAS: 667463-62-9 |
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| Catalog # | MBS515061 |
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| Order / More Info | LYS6K2 from MYBIOSOURCE INC. |
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| Product Specific References | 1. L Meijer et al. Chem. Biol. 2003 10:1255 2. AS Tseng et al. Chem. Biol. 2006 13:957 3. A Chebel et al. Leuk. Lymphoma 2009 50:2049 |
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