| 产品详情 |
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| Antigenic Specificity | LOXL2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat, mouse |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | WB, IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human LOXL2 polyclonal antibody for WB, IHC. Lysyl oxidase homolog 2 (EC1.4.3.13; also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, or Lysyl oxidase-related protein WS9-14) is encoded by the LOXL2 gene (also known as LOR2 or WS9-14) in human. LOXL2 protein catalyzes oxidative deamination of target lysine residues to allysine. Secreted LOXL2 protein mediates cross-linking of extracellular matrix proteins by targeting lysine residues in fibrous collagen and elastin in precursors. It is also found in the nucleus where it acts as a transcription corepressor by targeting trimethylated histone H3 Lys3 (H3K4me3). Its involvement in other biological processes inclucdes epithelial to mesenchymal transition (EMT) and repression of E-cadherin expression. |
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| Immunogen | Recombinant Protein |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 4017, UniProt: Q9Y4K0 |
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| Catalog # | CABT-B1580 |
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| Price | |
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| Order / More Info | LOXL2 Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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| 产品资料 |
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