| 产品详情 |
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| Antigenic Specificity | Caspase-8 (Active) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | 0.5 mg/ml |
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| Applications | Western blot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase-8 (Active) Antibody. Caspase-8, a member of the caspase-family of proteases, plays a key role in mediating Fas (CD95) and TNF induced apoptosis. Caspase-8 is synthesized as inactive pro-enzyme and activation of the enzyme involves proteolytic cleavage that leads to the release of the active p18 and p10 subunits. Activated caspase-8 is able to cleave and activate downstream caspases, such as caspase-3, -6, -7 and a death agonist member of the Bcl-2/Bcl-xL family, Bid, leading to apoptosis. |
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| Immunogen | Synthetic peptide corresponding to residues surrounding amino acid 392 of mouse caspase-8 |
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| Other Names | CASP8 , MGC78473 , CASP-8, MACH, procaspase-8, MCH5, ALPS2B, FLICE, CAP4, EC 3.4.22.61 |
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| Gene, Accession # | Gene ID: 12370, Accession: BC006737 |
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| Catalog # | 3259-100 |
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| Price | |
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| Order / More Info | Caspase-8 (Active) Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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