| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | mouse, rat, human |
|---|
| Isotype | n/a |
|---|
| Format | affinity purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Caspase-10 is a DED (death effector domain)-containing caspase and functions as an initiator caspase in Fas/TNF induced apoptosis. Four isoforms of caspase-10 have been identified: caspase-10a (Mch4), caspase-10b (FLICE2), caspase-10c and caspase-10d. They have the same prodomain but different mature large and small subdomains. Upon death ligand-receptor binding, caspase-10 is coupled to the multimeric Fas/TNF receptor complex via DED/FADD adaptor interaction. This complex processes procaspase-10 into a large active fragment and a small fragment. Cleaved caspase-10 further processes other caspase members, including caspase-3 and caspase-7, to initiate a caspase cascade, leading to apoptosis.Synonyms: CASP10 , MCH4, Caspase 10, FLICE2, CASP 10, ICE like apoptotic protease 4 |
|---|
| Immunogen | Recombinant protein of human CASP10 |
|---|
| Other Names | xCaspase-10|alps2|caspace-10|caspase-10|flice2|mch4|xCaspace-10|ALPS2|FLICE2|MCH4 |
|---|
| Gene, Accession # | Gene ID: 843 |
|---|
| Catalog # | ABIN1512671 |
|---|
| Price | |
|---|
| Order / More Info | Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|