| 产品详情 |
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| Antigenic Specificity | Epstein-Barr Virus |
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| Clone | cocktail |
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| Host Species | Mouse |
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| Reactive Species | n/a |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:25-1:50 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Epstein-Barr Virus Antibody Cocktail. Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. |
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| Immunogen | n/a |
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| Other Names | EBV |
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| Gene, Accession # | n/a |
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| Catalog # | MA5-12172 |
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| Price | |
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| Order / More Info | Epstein-Barr Virus Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12665622 |
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