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| Product Name | AZ 5704 |
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| Description | Potent and selective ATM kinase inhibitor (IC50 = 0.6 nM in an enzyme inhibition assay). Exhibits > 600-fold selectivity for ATM over other kinases. Inhibits ATM kinase in an in vitro cellular assay (IC50 = 0.33 μM). Potentiates the antitumor effects of the topoisomerase 1 inhibitor irinotecan (CPT 11, Cat. No. 2688) in tumor bearing, immunocompromised mice. Orally bioavailable. Purity 98%. MW (observed): 434.47 |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 7-Fluoro-6-[6-(methoxymethyl)-3-pyridinyl]-4-[[(1S)-1-(1-methyl-1H-pyrazol-3-yl)ethyl]amino]-3-quinolinecarboxamide |
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| Gene, Accession, CAS # | CAS: 1941214-06-7 |
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| Catalog # | 6330/5 |
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| Price | |
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| Order / More Info | AZ 5704 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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