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Product Name | Co 101244 hydrochloride |
Description | Novel, potent and selective antagonist of GluN2B (formally NR2B)-containing NMDA receptors (IC50 values are 0.043, > 100 and > 100 μM for GluN1A/2B (NR1A/2B), GluN1A/2A (NR1A/2A) and GluN1A/2C (NR1A/2C) subunit combinations respectively). Displays neuroprotective effects in vivo and in vitro. Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions. Purity 99%. MW (observed): 377.91 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1-[2-(4-Hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]-4-piperidinol hydrochloride. PD 174494, Ro 63-1908 |
Gene, Accession, CAS # | CAS: 193356-17-1 |
Catalog # | 2456/10 |
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Order / More Info | Co 101244 hydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 18632800, 25071439, 25450957 |
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