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| Product Name | Hesperadin hydrochloride |
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| Description | ATP-competitive inhibitor of Aurora B kinase (IC50 = 250 nM). Prevents chromosome alignment and segregation; also induces polyploidy and prevents histone H3-Ser10 phosphorylation. Overrides the spindle assembly checkpoint and induces mitotic exit in monastrol - and taxol -treated HeLa cells. Purity 99%. MW (observed): 553.12 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[2,3-Dihydro-2-oxo-3-[(3Z)-phenyl[[4-(1-piperidinylmethyl)phenyl]amino]methylene]-1H-indol-5-yl]-ethanesulfonamide hydrochloride |
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| Gene, Accession, CAS # | CAS: 422513-13-1 |
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| Catalog # | 3988/50 |
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| Order / More Info | Hesperadin hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 12707311 |
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